"Republicans had a tough night last night. We lost great Senators in hard races. In Alaska and Mississippi, we continue to fight. There are clear lessons to be learned from the results. First, we should listen to what voters unmistakably said last night. Their priorities must always come first. Our job is to forcefully act on them. Senate Republicans have an opportunity and obligation to show our voters that we are fighting for them. In the Senate, we will aggressively oppose terrible ideas that drive our country toward the socialism Democrats embraced. Our commitment is to common sense. And our focus should not waiver from the top priority of driving down prices that have remained stubbornly too high. I’m here for the fight. I know my colleagues are too."

"Posted on X in October 2025 that Sununu's decision to run catapulted New Hampshire to "a top-tier U.S. Senate race."

"Democrats seem to want America to fail. Republicans are going to continue to fight for freedom, liberty, and continued American greatness. https://t.co/V3MPJB1TK6"

"Democrats say this is the future of their party: •Abolish ICE •Open the border •Raise taxes to pay for healthcare for illegal immigrants •Defund the police •Open the prisons •Men in women's sports •Sex change operations for children This can't be the future of our country."

"We are doing all we can to get out the votes in these key Senate races."

"Republicans are rooting out rampant Democrat fraud. - No taxpayer-funded healthcare for illegal immigrants - Tightened eligibility requirements for Medicaid - Work requirements for Medicaid & Food Stamps Democrats would rather protect thieves than American taxpayers."